Pakke Tiger Reserve lies in the foothills of the Eastern Himalaya in the East Kameng district of Arunachal Pradesh. It is considered one of the best protected national parks in the country, thanks to the commitment and dedication of the Forest Department field staff. Pakke is also known for its amazing sightings of four resident hornbill species.

The reserves elevations range from 100 to 2,000 m (330 to 6,560 ft) above msl. The terrain is rugged with mountainous ranges in the north and narrow plains and sloping hill valleys in the south. The sanctuary slopes southwards towards the river valley of the Brahmaputra River.[2] The area of Brahmaputra and Chittagong Hills, which includes Pakke and Namdapha Tiger Reserve, is the north-western limit of the Indochinese tiger's range, bordering the eastern limit of the Bengal tiger's range.
Pakke Wildlife Sanctuary lies in the undulating and hilly foothills of the Eastern Himalayas in Arunachal Pradesh's East Kameng District at altitude ranging from 150 to 2,000 m (490 to 6,560 ft). It is bounded by Bhareli or Kameng River in the west and north, and by Pakke River in the east. It is surrounded by contiguous forests on most sides.[citation needed] To the east lies Papum Reserve Forest with an area of 1,064 km2 (411 sq mi). Towards the south and south-east, the sanctuary adjoins reserve forests and Assam's Nameri National Park. To the west, it is bounded by Doimara Reserve Forest with an area of 216 km2 (83 sq mi) and Eaglenest Wildlife Sanctuary; and to the north by Shergaon Forest Division. Selective logging on a commercial scale occurred in the reserve forests until 1996
The area of Pakke Tiger Reserve was initially constituted as Pakhui Reserve Forest on 1 July 1966 and declared a game reserve on 28 March 1977. In 2001, it was renamed Pakhui Wildlife Sanctuary and became Pakhui Tiger Reserve on 23 April 2002 as the 26th Tiger Reserve under Project Tiger of the National Tiger Conservation Authority.